Bone Marrow Evaluation for Diagnosis and Monitoring Of Acute Myeloid Leukemia > 자유게시판

The analysis of acute myeloid leukemia (AML) may be made based mostly on peripheral blood or bone marrow blasts. On this evaluation, we'll talk about the function of bone marrow analysis and peripheral blood monitoring within the analysis, administration, and observe up of AML patients. For patients with circulating blasts, it's affordable to perform the necessary research needed for prognosis and threat stratification, together with multiparametric move cytometry, cytogenetics, and molecular analysis, on a peripheral blood specimen. The day 14 marrow is used to document hypocellularity in response to induction chemotherapy, however it's unclear if that evaluation is critical as it often does not affect immediate management. Currently, response assessments carried out at count restoration for evaluation of remission and measurable residual illness rely on bone marrow sampling. For monitoring of relapse, peripheral blood evaluation could also be sufficient, however the sensitivity of bone marrow testing is in some instances superior. While bone marrow analysis can actually be prevented particularly conditions, this cumbersome and uncomfortable procedure presently stays the de facto commonplace for response assessment.

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